Greater pressure pain threshold analgesia seen for hydromorphone than dronabinol and greater capsaicin and noncapsaicin ...

A noninvasive, home-based brain treatment with transcranial direct current stimulation (tDCS) can reduce pain severity, improve pain-related disability, and enhance endogenous pain modulation in women ...

This article examines emerging non-opioid strategies for chronic pain, from targeted ion-channel drugs and anti-inflammatory ...

Staying physically active improves pain modulation and reduces the risk of older adults developing chronic pain, according to new research by Kelly Naugle and colleagues at Indiana University-Purdue ...

How does the placebo effect work? A new study identifies the vlPAG brain region and endogenous opioid signaling as the keys to expectancy-driven pain relief.

The need to recognize and manage chronic nociplastic pain has become integral to rheumatology practice, as research over the past half-decade has affirmed that when central sensitization is present, ...

51.6 million Americans live with chronic pain. A new device created by USC biomedical engineers could help sufferers avoid the need for opioids. Image/Karolina Grabowska, Pexels. Chronic pain is a ...

NEW IBS research highlights persistent pain treatment gaps and points to peripheral nerve targets for future, safer therapies ...