Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

A series of recent physiology studies span from rare disease mechanisms to space-based biomedical advances. Findings include a new mouse model for myofibrillar myopathy type 6 that identifies ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Mrep accumulates in damaged muscle tissue and promotes muscle regeneration by acting on muscle satellite cells through activin A. While Mrep performs beneficial functions in normal muscle repair, in ...

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells. Similar to the instant kung fu ...