New research shows how certain orphan noncoding RNA — oncRNA — can be predictable enough to be a ‘bar code’ identifying ...
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AI is making CRISPR smarter and safer
Artificial intelligence is supercharging CRISPR genome editing, making it faster, more precise, and safer. From designing optimal guide RNAs to predicting and preventing off-target effects, AI tools ...
Researchers have built a series of CRISPR-based platforms that can switch endogenous genes on and, just as critically, dial the activation level up or down by adjusting a small-molecule dose. The work ...
Even without deep computational skills, scientists can use the CRISPRware program to quickly browse entire libraries of precomputed guide RNAs for six model organisms, zoom in on their gene or region ...
DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...
Scientists have gained tremendous control over the genome with CRISPR editing systems, that use a guide RNA molecule to ...
On June 11, 2025, the United States Court of Appeals for the Federal Circuit affirmed the Patent Trial and Appeal Board (PTAB) decision invalidating two patents owned by Agilent Technologies. The ...
CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...
RNA epigenetics also called Epitranscriptomics is an evolving field of research that explores chemical modifications on RNA and their impact on the cell and ...
< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...
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