Fred Hutch

Researchers uncover genetic sequence responsible for rare form of pancreatic cancer

SEATTLE — March 12, 2007 — Pancreatic ductal adenocarcinoma is an almost uniformly fatal disease regardless of the stage at time of diagnosis. However, a small percentage of patients develop a form of ...
Nature

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

Sensing of nucleic acids is crucial to antiviral defense. Unlike pathogen-associated molecular patterns (PAMPs) of bacterial origin that are foreign to the host, nucleic acids are vital to both host ...
Labroots

The evolution of carbon fixation: Studying Form I Rubisco using ancestral sequence reconstruction and mass photometry

Up to now, the evolutionary trajectory of the most prevalent CO2-fixing enzyme – Rubisco Form I, has been difficult to study. The Rubisco found in today’s plants and algae has 8 small subunits (SSU) ...
CNN

Genetic sequence of coronavirus was submitted to US database two weeks before China’s official disclosure, documents show

The genetic sequence of SARS-CoV-2, the virus that causes Covid-19, was submitted to a National Institutes of Health database two weeks before its release by the Chinese government, according to ...